PCR amplification of rearranged genomic variable regions of immunoglobulin genes
US6258529A · kind A · utility
5Cited by
2References
5Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 1, 1994 |
| Grant date | Jul 10, 2001 |
| Priority date | — |
| Expiry date | Dec 1, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/158
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention features methods for isolating immunoglobulin variable region genes, and the use of these genes in the production of chimeric and isotype switched antibodies. The invention also features substantially pure DNA encoding a variable region of the antibody produced by hybridoma cell line HNK-20, and chimeric antibodies containing this variable region.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.