Pressure-controlled nucleic acid hybridization
US6258534A · kind A · utility
5Cited by
5References
16Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 5, 1998 |
| Grant date | Jul 10, 2001 |
| Priority date | — |
| Expiry date | Mar 5, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6813
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A method of hybridizing a first nucleic acid to a second nucleic acid at least partially complementary to the first nucleic acid by (1) providing a sample vessel and pressure controller for the vessel; and (2) contacting the first and second nucleic acids within the vessel at a pressure above ambient pressure that is effective to enhance hybridization of the first and second nucleic acids.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.