Production of polyketides in bacteria and yeast
US6258566A · kind A · utility
8Cited by
8References
17Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 21, 1999 |
| Grant date | Jul 10, 2001 |
| Priority date | — |
| Expiry date | Oct 21, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Hybrid and novel polyketide synthases (PKSs) and polyketides are produced by use of a multiple vector system. The combinatorial possibilities offered by placing the various catalytic activities of PKS systems on separate vectors permits the construction of improved libraries of PKS and polyketides. In addition, polyketides can be produced in hosts that ordinarily do not produce polyketides by supplying, along with an expression system for the desired PKS, an expression system for holo acyl carrier protein (ACP) synthase.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.