Patent · US Expired

Production of optically active 2-substituted tetrahydropyran-4-ones

US6258574A · kind A · utility

1Cited by
5References
11Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJul 23, 1999
Grant dateJul 10, 2001
Priority date—
Expiry dateJul 23, 2019

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12P17/06
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

Optically active 2-substituted tetrahydropyran-4-ols or esters thereof may be prepared using esterases or hydrolases from the corresponding racemic mixtures of esters or alcohols. This provides a route to the corresponding optically active ketones. The racemic mixtures are preferably in the cis-form. such mixtures may be produced by-reacting but-3-ene-1-ol with an aldehyde in the presence of an acid.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.