Materials and method for treating or preventing pathogenic fungal infection

US6258823A · kind A · utility

Assignee

• Ariad Pharmaceuticals, Inc. · US

Inventors

• Dennis A. Holt · Downingtown, US
• Terence P. Keenan · Cambridge, US
• Timothy Piers Clackson · Cambridge, US
• Leonard W. Rozamus · Andover, US
• Wu Yang · Ann Arbor, US
• Michael Z. Gilman · Newton, US

Key dates

• Filing date: Nov 2, 1998
• Grant date: Jul 10, 2001
• Expiry date: Nov 2, 2018

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D498/16
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

This invention concerns derivatives of rapamycin and their antifungal uses. Also disclosed are materials and methods relevant to the identification of non-immunosuppressive antifungal rapamycin derivatives.