Purified telomerose

US6261556A · kind A · utility

Assignee

• Geron Corporation · US

Inventors

• Scott L. Weinrich · San Francisco, US
• Edward M. Atkinson, III · Seattle, US
• Serge Lichtsteiner · Cupertino, US
• Alain P. Vasserot · South San Francisco, US
• Ronald A. Pruzan · Palo Alto, US
• James Kealey · Sebastopol, US

Key dates

• Filing date: Oct 18, 1999
• Grant date: Jul 17, 2001
• Expiry date: Oct 18, 2019

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K39/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

This invention provides purified human telomerase and methods of purifying it. The methods involve the use of several sequential steps, including the use of a first matrix that binds molecules bearing negative charges, a matrix that binds molecules bearing positive charges, a second matrix that binds molecules bearing negative charges, an affinity purification step and a matrix that separates molecules according to their size.