Retro-, inverso- and retro-inverso synthetic peptide analogues

US6261569A · kind A · utility

Assignee

• Deakin Research Limited · AU

Inventors

• Alfio Comis · Parramatta, AU
• Margaret Isabel Tyler · Hornsby, AU
• Peter Fischer · Oslo, NO

Key dates

• Filing date: Aug 12, 1997
• Grant date: Jul 17, 2001
• Expiry date: Aug 12, 2017

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S530/826
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Synthetic peptide antigen analogues of native peptide antigens with partial or complete retro, inverso or retro-inverso modifications are provided. When administered as an immunogen to an immunocompetent host the synthetic peptide antigen analogues induce the production of antibodies which recognize the native peptide antigen. Uses of these analogues, vaccines and methods of preparing vaccines comprising these antigen analogues, and antibodies generated using these antigen analogues are also provided.