Enzymatic oxidative deamination process

US6261810A · kind A · utility

Assignee

• Bristol-Myers Squibb Company · US

Inventors

• Ramesh N. Patel · Bound Brook, US
• Amit Banerjee · Yardley, US
• Venkata B. Nanduri · East Brunswick Township, US
• Laszlo J. Szarka · East Brunswick Township, US
• Shankar Swaminathan · Braunschweig, DE
• John J. Venit · New Brunswick, US
• Jerome L. Moniot · Richboro, US
• David A. Lust · Roosevelt, US
• Sushil K. Srivastava

Key dates

• Filing date: Aug 31, 1999
• Grant date: Jul 17, 2001
• Expiry date: Aug 31, 2019

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K38/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention concerns an enzymatic oxidative deamination process of a dipeptide monomer to prepare an intermediate useful to prepare compounds having endopeptidase and angiotensin converting enzyme inhibition activity.