Pharmaceutical compositions containing cyclosporin as the active agent

US6262022A · kind A · utility

Assignee

• Novartis AG · CH

Inventors

• Birgit Hauer · Lahr (Eifel), DE
• Armin Meinzer · Glückstadt, DE
• Ulrich Posanski · Glückstadt, DE
• Jacky Vonderscher · Riedisheim, FR

Key dates

• Filing date: Jan 19, 2000
• Grant date: Jul 17, 2001
• Expiry date: Jan 19, 2020

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C11C3/06
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Pharmaceutical compositions comprising a cyclosporin in a novel galenic formulations for oral administration. The compositions typically comprise a cyclosporin, 1,2-propylene glycol, a mixed mono-, di- and tri-glyceride and a hydrophilic surfactant. Further a refined glycerol-transesterified corn oil is provided representing a mixed mono-, di- and tri-glyceride suitable for the novel formulation. Dosage forms include in particular oral dosage forms.