Patent · US Expired

Pseudopolymorphic forms of 2-[2-[4-[Bis(4-fluorophenyl)methyl]-1-piperazinyl]ethoxy]acetic acid dihydrochloride

US6262057A · kind A · utility

2Cited by

3References

6Claims

0Family size

Assignee

UCB S.A. · BE

Inventors

Monique Berwaer · Montigny-le-Tilleul, BE
Guy Bodson · Virton, BE
Michel Deleers · Linkebeek, BE
Charles Dogimont · Brussels, BE
Domenico Fanara · Wanze, BE
Jacques Timmermans · Tubize, BE

Key dates

Filing date	May 23, 2000
Grant date	Jul 17, 2001
Priority date	—
Expiry date	May 23, 2020

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P43/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to new pseudopolymorphic forms of 2-[2-[4-[bis(4-fluorophenyl)methyl]-1-piperazinyl]ethoxy]acetic acid dihydrochloride, namely, anhydrous 2-[2-[4-[bis(4-fluorophenyl)methyl]-1-piperazinyl]ethoxy]acetic acid dihydrochloride and 2-[2-[-bis(4-fluorophenyl)methyl]-1-piperazinyl]ethoxy]acetic acid dihydrochloride monohydrate. It also relates to processes for the preparation of these pseudopolymorphic forms and to pharmaceutical compositions containing them.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.