Methods of treating immunopathologies using polyunsaturated fatty acids

US6262119A · kind A · utility

Assignees

• Peptide Technology Ltd. · AU
• Women's and Children's Hospital Adelaide · AU

Inventors

• Antonio Ferrante · Piedimonte Matese, IT
• Alfred Poulos · Adelaide, AU
• Michael Joseph Pitt · Chatswood, AU
• Christopher Easton · Adelaide, AU
• Merilyn Sleigh · Fawn Drive, AU
• Deborah Rathjen · Forbes, AU
• Fred Widmer · Forbes, AU

Key dates

• Filing date: Apr 12, 1999
• Grant date: Jul 17, 2001
• Expiry date: Apr 12, 2019

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P37/08
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Method of treating or ameliorating symptoms of T-cell mediated disease wherein a composition comprising a therapeutically effective amount of a polyunsaturated fatty acid and a pharmaceutically acceptable carrier is administered to the patient. The polyunsaturated fatty acid contains 18-25 carbon atoms, 1-6 double bonds and has 1 or 2 substitutions selected from .beta. oxa, .gamma. oxa, .beta. thia and .gamma. thia, based on the fatty acid acyl carbon atom, or the polyunsaturated fatty acid contains 16-26 carbon atoms, 3-double bonds and is covalently coupled at the carboxylic acid group to an amino acid.