Hydroxamic acid polymers formed from primary amide polymers

US6262183A · kind A · utility

Assignee

• CYTEC TECHNOLOGY CORP. · US

Inventors

• Abraham J. Domb · Baltimore, US
• Robert S. Langer · Newton, US
• Ernest G. Cravalho · Wellesley, US
• Gershon Golomb · Beer Sheva, IL
• Edith Mathiowitz · Brookline, US
• Cato T. Laurencin · Philadelphia, US

Key dates

• Filing date: Mar 28, 1994
• Grant date: Jul 17, 2001
• Expiry date: Mar 28, 2014

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C08F2800/10
• WIPO field: Macromolecular chemistry, polymers
• WIPO sector: Chemistry

Abstract

Hydroxamic acid polymers which are comprised of hydroxamic groups and carboxylic acid groups wherein the carboxylic acid groups constitute less than about 3% of the functional groups. The polymers hereof are also especially useful in biomedical applications because, for example, the low concentration of carboxylic acid groups decreases the incidence of bioincompatibility. Additionally, the polymers exhibit anticoagulant activity, urease inhibition activity, metal chelating activity and ion exchange activity.