DNA and amino acid sequence specific for natural killer cells

US6262244A · kind A · utility

Assignees

• Regents of the University of Minnesota · US
• Novartis AG · CH

Inventors

• Jeffrey P. Houchins · Lino Lakes, US
• Toshio Yabe · Chiba, JP
• Cynthia M. McSherry · Maple Grove, US
• Fritz H. Bach · Madison, US
• Erhard Hofer · Wien, AT

Key dates

• Filing date: Oct 13, 1995
• Grant date: Jul 17, 2001
• Expiry date: Oct 13, 2015

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K48/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Proteins expressed in NK and some T cells and being transmembrane molecules with Type II membrane protein structure, the extracellular part of the receptor being characterized by a C-type animal lectin domain, DNA sequences encoding such proteins and antibodies against the extracellular part of the transmembrane protein which can activate NK and T cells.