Patent · US Expired

Stereoselective ring opening reactions

US6262278A · kind A · utility

19Cited by
22References
29Claims
0Family size

Assignee

Inventors

Key dates

Filing dateAug 14, 1998
Grant dateJul 17, 2001
Priority date
Expiry dateAug 14, 2018

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07C2601/16
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The present invention relates to a process for stereoselective or regioselective chemical synthesis which generally comprises reacting a nucleophile and a chiral or prochiral cyclic substrate in the presence of a non-racemic, chiral catalyst to produce a stereoisomerically- and/or regioisomerically-enriched product. The present invention also relates to hydrolytic kinetic resolutions of racemic and diastereomeric mixtures of epoxides.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.