Human genes and gene expression products

US6262333A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Wilson Endege · Norwood, US
• Kathleen Steinmann · Lincoln, US
• Jon Astle · Taunton, US
• Christopher Burgess · Westwood, US
• Steven Bushnell · Medfield, US
• Eddie Carroll · Norwood, US
• Theodore Catino · Attleboro, US
• Adnan Derti · Boston, US
• Donna Ford · Plainville, US
• Marcia Lewis · Cohasset, US
• John E. Monahan · Walpole, US
• Robert Schlegel · Waltham, US

Key dates

• Filing date: Jun 8, 1999
• Grant date: Jul 17, 2001
• Expiry date: Jun 8, 2019

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K38/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

This invention relates to novel human genes, to proteins expressed by the genes, and to variants of the proteins. The invention also relates to diagnostic assays and therapeutic agents related to the genes and proteins, including probes, antisense constructs. and antibodies. The subject nucleic acids have been found to be differentially regulated in tumor cells, particularly colon cancer cell lines and/or tissue.