Transgenic animal with recombinant vascular endothelial growth factor B (VEGF-B DNA) and uses thereof

US6262337A · kind A · utility

Assignee

• LUDWIG INSTITUTE FOR CANCER RESEARCH LTD · GB

Inventors

• Gabriel von Euler · Stockholm, SE
• Karin Aase · Stockholm, SE
• Christer Betsholtz · Uppsala, SE
• Ulf Eriksson
• Milos Pekny · Handen, SE
• Samuel Gebre-Medhin · Göteborg, SE
• Xuri Li · Stockholm, SE

Key dates

• Filing date: Feb 18, 1998
• Grant date: Jul 17, 2001
• Expiry date: Feb 18, 2018

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A01K2267/03
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

Transgenic animals containing recombinant DNA with modified nucleotide sequence from the vascular endothelial growth factor B (VEGF-B) gene, cells and methods for producing such animals, and methods of using them to assay substances for VEGF-B-like activity.