Methods and compositions for identifying and modulating ctionprotein-interactions
US6265174A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Sep 9, 1998 |
| Grant date | Jul 24, 2001 |
| Priority date | — |
| Expiry date | Sep 9, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to methods and compositions for the identification and modulation of protein-protein interactions. Specifically, the invention relates to methods and compositions for efficient, sensitive, high-throughput CadC-based screens for the identification of peptides involved in protein-protein interactions, including, but not limited to, peptides comprising amino acid sequences involved in receptor dimerization. The invention further relates to methods and compositions for efficient, sensitive, high-throughput CadC-based screens for compounds which modulate protein-protein interactions, such as, for example, modulation of interactions between protein sequences involved in receptor interactions, e.g., dimerization.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.