Polynucleotides encoding chemokine receptor 88C
US6265184A · kind A · utility
31Cited by
4References
11Claims
0Family size
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Key dates
| Filing date | Dec 20, 1995 |
| Grant date | Jul 24, 2001 |
| Priority date | — |
| Expiry date | Dec 20, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/43
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides polynucleotides that encode the chemokine receptors 88-2B or 88C and materials and methods for the recombinant production of these two chemokine receptors. Also provided are assays utilizing the polynucleotides which facilitate the identification of ligands and modulators of the chemokine receptors. Receptor fragments, ligands, modulators, and antibodies are useful in the detection and treatment of disease states associated with the chemokine receptors such as atherosclerosis, rheumatoid arthritis, tumor growth suppression, asthma, and other inflammatory conditions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.