Methods for expressing nucleic acid sequences using nucleic acid constructs comprising hypoxia response elements
US6265390A · kind A · utility
5Cited by
3References
82Claims
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Key dates
| Filing date | Feb 22, 1999 |
| Grant date | Jul 24, 2001 |
| Priority date | — |
| Expiry date | Feb 22, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2830/85
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Nucleic acid constructs comprising hypoxia response elements in operable linkage with a coding sequence of a gene of interest, and methods for expressing a nucleic acid sequence using the constructs, are disclosed. In particular, such nucleic acid constructs comprise genes encoding prodrug activation systems or cytokines.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.