Patent · US Expired

Oxindole derivatives

US6265411A · kind A · utility

46Cited by
14References
19Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 6, 1998
Grant dateJul 24, 2001
Priority date
Expiry dateNov 6, 2018

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D403/14
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The invention relates to compounds of formula (I), ##STR1## PA1 wherein: PA2 R.sup.2 represents hydroxy, halogeno, C.sub.1-3 alkyl, C.sub.1-3 alkoxy, C.sub.1-3 alkanoyloxy, trifluoromethyl, cyano, amino, nitro, C.sub.2-4 alkanoyl, C.sub.1-4 alkanoylamino, C.sub.1-4 alkoxycarbonyl, C.sub.1-4 alkylthio, C.sub.1-4 alkylsulphinyl, C.sub.1-4 alkylsulphonyl, carbamoyl, N--C.sub.1-4 alkylcarbamoyl, N,N-di(C.sub.1-4 alkyl)carbamoyl, aminosulphonyl, N--C.sub.1-4 alkylaminosulphonyl, N,N-di(C.sub.1-4 alkyl)aminosulphonyl, C.sub.1-4 alkylsulphonylamino, or a group R.sup.4 X.sup.1 wherein X.sup.1 represents a direct bond, C.sub.2-4 alkanoyl, --CONR.sup.5 R.sup.6 --, --SO.sub.2 NR.sup.7 R.sup.8 -- or --SO.sub.2 R.sup.9 -- (wherein R.sup.5 and R.sup.7, each independently represents hydrogen or C.sub.1-2 alkyl and R.sup.6, R.sup.8 and R.sup.9 each independently represents C.sub.1-4 alkyl and wherein R.sup.4 is linked to R.sup.6, R.sup.8 or R.sup.9) and R.sup.4 represents an optionally substituted group selected from phenyl and a 5 or 6-membered heterocyclic group; n is an integer from 0 to 4, R.sup.1 represents hydrogen, C.sub.1-4 alkyl, C.sub.1-4 alkoxymethyl, di(C.sub.1-4 alkoxy)methyl or C.sub…

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.