Method for treating congestive heart failure
US6265429A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Oct 19, 1999 |
| Grant date | Jul 24, 2001 |
| Priority date | — |
| Expiry date | Oct 19, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to methods for treating congestive heart failure in a mammal by administering a congestive heart failure treating amount of a compound which inhibits phosphodiesterase type IV and the production of tumor necrosis factor, such as, for example, a substituted indazol derivative, e.g., of the formula ##STR1## or a pharmaceutically acceptable salt thereof, wherein R, R.sub.1 and R.sub.2 are as defined herein. The invention further relates to pharmaceutical compositions for the treatment of congestive heart failure comprising a congestive heart failure treating amount of a compound which inhibits phosphodiesterase type IV and the production of tumor necrosis factor, such as, for example, a substituted indazol derivative, e.g., of formula (I) herein, or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable vehicle, diluent or carrier.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.