ABO histo-blood group O alleles of the baboon
US6265557A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | May 9, 1997 |
| Grant date | Jul 24, 2001 |
| Priority date | — |
| Expiry date | May 9, 2017 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA01K2217/075
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
This invention relates to histo-blood group O alleles of baboon. The major O allele retains identifying sequence characteristics of the baboon A allele. Other alleles, including a B-like allele, are also disclosed herein. The O alleles of baboon are closer in sequence similarity to the baboon A and B alleles than are any of the baboon ABO alleles to the human alleles of the ABO locus. This invention also provides materials and methods for identifying O alleles, and carriers of O alleles, as well as methods for producing baboons and baboon cells, tissues, and organs having a group O phenotype. Group O baboons, cells, tissues, and organs of the invention are useful for xenotransplantation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.