Intermediary compounds for the hemisynthesis of taxanes and preparation processes therefor
US6265587A · kind A · utility
5Cited by
3References
23Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 27, 1998 |
| Grant date | Jul 24, 2001 |
| Priority date | — |
| Expiry date | Apr 27, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F7/1892
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to new intermediates for the semisynthesis of taxanes and their preparation processes. It relates to derivatives of oxazolidines or oxazolidinones, as well as to new derivatives of baccatine III. The general process for the synthesis of taxanes according to the invention enables to obtain a product such as PACLITAXEL in only five steps from products available in the market, compared to nine steps in general, for processes of the prior art.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.