Thio-substituted pentanedioic acid derivatives
US6265609A · kind A · utility
49Cited by
68References
35Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 12, 1999 |
| Grant date | Jul 24, 2001 |
| Priority date | — |
| Expiry date | Jan 12, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C323/52
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relate to thio-substituted pentanedioic acid derivatives that inhibit N-Acetylated .alpha.-Linked Acidic Dipeptidase (NAALADase) enzyme activity, pharmaceutical compositions comprising the same, and methods of using the same to inhibit NAALADase enzyme activity, to effect neuronal activities, to inhibit angiogenesis, and to treat glutamate abnormalities, compulsive disorders and prostate diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.