Specific inhibitors of DNA methyl transferase
US6268137A · kind A · utility
8Cited by
2References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 8, 1998 |
| Grant date | Jul 31, 2001 |
| Priority date | — |
| Expiry date | Dec 8, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/53
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides novel mechanism-based inhibitors of DNA methyltransferase enzyme, and diagnostic and therapeutic uses for the same. The novel inhibitors according to the invention form stable, noncovalent complexes with DNA methyltransferase enzyme in a manner which is independent of S-adenosylmethionine.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.