Analytical methods and materials for nucleic acid detection
US6268146A · kind A · utility
123Cited by
73References
36Claims
0Family size
Assignee
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Key dates
| Filing date | Nov 22, 1999 |
| Grant date | Jul 31, 2001 |
| Priority date | — |
| Expiry date | Nov 22, 2019 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/24
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Mass spectrometric, absorbance spectroscopic and fluorescence spectroscopic processes are disclosed to detect the depolymerization of a nucleic acid hybrid in order to qualitatively and quantitatively assay for the presence of a predetermined nucleic acid target. Applications of those processes include the detection of single nucleotide polymorphisms, identification of single base changes, speciation, determination of viral load, genotyping, medical marker diagnostics, and the like, including multiplexed assays.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.