Isolated nucleic acid encoding nucleotide pyrophosphorylase

US6268177A · kind A · utility

Assignee

• SmithKline Beecham Limited · US

Inventors

• Sanjoy Biswas · Paoli, US
• James Raymond Brown · Berwyn, US
• Martin Karl Russel Burnham · Norristown, US
• Alison Francis Chalker · Trappe, US
• David John Holmes · West Chester, US
• Karen Anne Ingraham · Auburn, US
• Thomas B Mathie · Eagleville, US
• Richard Lloyd Warren · Grantsville, US
• Magdalena Zalacain · West Chester, US

Key dates

• Filing date: Apr 2, 1999
• Grant date: Jul 31, 2001
• Expiry date: Apr 2, 2019

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention provides ndp polypeptides and polynucleotides encoding ndp polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ndp polypeptides to screen for antibacterial compounds.