Patent · US Expired

Pharmaceutical composition for treatment of hepatic diseases

US6268336A · kind A · utility

11Cited by
1References
6Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 18, 1998
Grant dateJul 31, 2001
Priority date
Expiry dateDec 18, 2018

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K38/1816
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to a pharmaceutical composition for treatment of hepatic diseases which comprises erythropoietin as an active ingredient to reduce excess iron ions in the liver of a mammal with hepatic diseases, thus improving hepatic functions of said mammal. According to the present pharmaceutical composition with erythropoietin as an active ingredient, excess iron ions in the liver of a mammal with hepatic diseases can be decreased, so it is effective for treatment of chronic hepatitis, hepatic carcinoma, hepatocirrhosis etc. due to excess iron ions. Further, patient's anemia accompanying venesection can be prevented while excretion of excess iron ions can be promoted by using the venesection therapy in combination with the administration of said pharmaceutical composition. Furthermore, the pharmaceutical composition of the present invention is administered into a patient with chronic hepatitis C for whom IFN therapy is not effective to improve hepatic functions after which conventional IFN therapy is conducted whereby its therapeutic effect on said hepatitis can be expected.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.