Patent · US Expired

Combination therapy employing ileal bile acid transport inhibiting benzothiepines and HMG Co-A reductase inhibitors

US6268392A · kind A · utility

19Cited by
7References
49Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 9, 1998
Grant dateJul 31, 2001
Priority date
Expiry dateMar 9, 2018

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC08G65/329
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Provided are novel benzothiepines, derivatives, and analogs thereof; pharmaceutical compositions containing them; and methods of using these compounds and compositions in medicine, particularly in the prophylaxis and treatment of hyperlipidemic conditions such as those associated with atherosclerosis or hypercholesterolemia, in mammals. Also provided are compositions and methods for combination therapy employing ileal bile acid transport inhibitors and EG Co-A reductase inhibitors for the treatment of hyperlipidemic conditions.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.