Patent · US Expired

Compounds and methods for treating mitochondria-associated diseases

US6268398A · kind A · utility

117Cited by
5References
40Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 23, 1999
Grant dateJul 31, 2001
Priority date
Expiry dateApr 23, 2019

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P43/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Compounds, compositions and methods are disclosed for treating mitochondria-associated diseases, such as cancer, psoriasis, stroke, Alzheimer's Disease and diabetes. The compounds of this invention have structure (I) below, including stereoisomers, prodrugs and pharmaceutically acceptable salts thereof, wherein Ar and L are as defined herein. The methods of this invention are directed to treating a mitochondria-associated disease by administering to a warm-blooded animal in need thereof an effective amount of a compound of structure (I), typically in the form of a pharmaceutical composition. ##STR1##

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.