Chemokine receptor 88-C
US6268477A · kind A · utility
31Cited by
3References
1Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 7, 1996 |
| Grant date | Jul 31, 2001 |
| Priority date | — |
| Expiry date | Jun 7, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/43
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides polynucleotides that encode the chemokine receptors 88-2B or 88C and materials and methods for the recombinant production of these two chemokine receptors. Also provided are assays utilizing the polynucleotides which facilitate the identification of ligands and modulators of the chemokine receptors. Receptor fragments, ligands, modulators, and antibodies are useful in the detection and treatment of disease states associated with the chemokine receptors such as atherosclerosis, rheumatoid arthritis, tumor growth suppression, asthma, viral infection, AIDS, and other inflammatory conditions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.