Prodrug activation using catalytic antibodies
US6268488A · kind A · utility
97Cited by
1References
15Claims
0Family size
Inventors
Key dates
| Filing date | May 25, 1999 |
| Grant date | Jul 31, 2001 |
| Priority date | — |
| Expiry date | May 25, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a compound that includes an active therapeutic agent attached to a blocking moiety that is sensitive to the catalytic action of molecules having retro-aldol and retro-Michael catalytic activity, methods for making such compounds and methods of converting such compounds to active therapeutic agents using molecules having aldolase activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.