Patent · US Expired

Modified factor VIII cDNA

US6271025A · kind A · utility

17Cited by

0References

6Claims

0Family size

Assignee

Aventis Behring GmbH · DE

Inventors

Claude Negrier · Irigny, FR
Jean-Luc Plantier · Val-de-Reuil, FR

Key dates

Filing date	Mar 16, 2000
Grant date	Aug 7, 2001
Priority date	—
Expiry date	Mar 16, 2020

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P7/04
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

A modified Factor VIII cDNA is described comprising deletion of the B-domain and insertion of at least one truncated Factor IX intron 1 in the Factor VIII cDNA. The modified Factor VIII cDNA may be used for the production of a high yield of Factor VIII in vitro. The modified Factor VIII cDNA may be incorporated into a vector for gene therapy.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.