Process of making cationic lipid-nucleic acid complexes
US6271208A · kind A · utility
57Cited by
3References
35Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Feb 26, 1999 |
| Grant date | Aug 7, 2001 |
| Priority date | — |
| Expiry date | Feb 26, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K48/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention is related to a method for preparing an homogenous suspension of stable lipid-nucleic acid complexes or particles, comprising: a) combining one or more cationic lipids, one or more colipids, and one or more stabilizing additives to form a lipid suspension, b) combining the lipid suspension with a nucleic acid to form a complex or a particle, and optionally c) subjecting the complex or particle to a sizing procedure. It also concerns an homogenous suspension produced notably by the above method.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.