Sulfated oligosaccharides having anticoagulant/antithrombotic activity

US6271215A · kind A · utility

Assignee

• The Australian National University · AU

Inventors

• Christopher Richard Parish · Campbell, AU
• William Butler Cowden · Campbell, AU

Key dates

• Filing date: Nov 15, 1999
• Grant date: Aug 7, 2001
• Expiry date: Nov 15, 2019

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P7/02
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A method for the anticoagulant and/or antithrombotic treatment of a human or other warm-blooded animal patient in need of such treatment, comprises administration to the patient of an effective amount of at least one sulfated oligosaccharide, wherein the oligosaccharide has the general formula I: EQU R.sub.1 --(R.sub.x).sub.n --R.sub.2 (I) wherein R.sub.1 and R.sub.2 and each R.sub.x represents a monosaccharide unit, all of which may be the same or different, adjacent monosaccharide units being linked by 1.fwdarw.2, 1.fwdarw.3, 1.fwdarw.4 and/or 1.fwdarw.6 glycosidic bonds and n is an integer of from 1 to 6.