Patent · US Expired

Methods for controlling gram negative bacteria in mammals with bicyclo spiroether compounds

US6271256A · kind A · utility

1Cited by
9References
20Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 30, 1999
Grant dateAug 7, 2001
Priority date
Expiry dateNov 30, 2019

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K31/35
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Methods for controlling growth of gram negative bacteria, such as Helicobacter pylori, which are agents associated with disorders of the gastrointestinal tract of a mammal are described. They include administering a therapeutically effective amount of a polyether ionophore antibiotic to a mammal, such that growth of gram negative bacteria which are agents associated with disorders of the gastrointestinal tract of a mammal is controlled. Packaged pharmaceutical compositions for controlling gram negative bacteria are also described. The packaged compositions include a container holding a therapeutically effective amount of a pharmaceutical composition for controlling gram negative bacteria which are agents associated with disorders of the gastrointestinal tract of a mammal and instructions for using the pharmaceutical composition for control of the gram negative bacteria, such that growth of gram negative bacteria which are agents associated with disorders of the gastrointestinal tract of a mammal is controlled. The pharmaceutical composition includes at least one polyether ionophore antibiotic or a bicyclic spiroether.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.