Use of idebenone and analogues against .beta. amyloid induced cytotoxicity
US6271266A · kind A · utility
27Cited by
1References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 9, 1998 |
| Grant date | Aug 7, 2001 |
| Priority date | — |
| Expiry date | Nov 9, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/122
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A compound of the formula: ##STR1## wherein R.sup.1 represents a lower alkyl; R.sup.2 represents H, an optionally substituted alkyl or an optionally substituted alkenyl; R.sup.3 and R.sup.4 each represents an optionally substituted lower alkyl or a lower alkoxy, or R.sup.3 and R.sup.4 form, taken together, an optionally substituted butadienylene; and X.sup.1 and X.sup.2 each represents an optionally esterified or etherified hydroxy, or a salt thereof is useful for protecting cells from the cytotoxicity of .beta.-amyloid protein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.