Method for producing triazolinethione derivatives

US6271389A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Reinhard Lantzsch · Leverkusen, DE
• Manfred Jautelat · Burscheid, DE
• Achim Hupperts · Düsseldorf, DE
• David Erdman · Neunburg vorm Wald, DE

Key dates

• Filing date: Apr 3, 2000
• Grant date: Aug 7, 2001
• Expiry date: Apr 3, 2020

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D249/12
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

According to a novel process, it is possible to prepare triazolinethione derivatives of the formula ##STR1## in which R.sup.1 and R.sup.2 are each as defined in the description by PA1 a) reacting hydrazine derivatives of the formula ##STR2## PA1 with carbonyl compounds of the formula ##STR3## PA1 in which R.sup.3 and R.sup.4 are each as defined in the description PA1 with potassium thiocyanate, sodium thiocyanate or ammonium thiocyanate, PA1 if appropriate in the presence of a diluent and if appropriate in the presence of an acid, and PA1 b) reacting the resulting triazolidinethione derivatives of the formula ##STR4## PA1 with formic acid, if appropriate in the presence of a catalyst and if appropriate in the presence of a diluent. The triazolidinethione derivatives of the formula (V) are novel.