Medical devices having improved antimicrobial/antithrombogenic properties
US6273875A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Aug 17, 1998 |
| Grant date | Aug 14, 2001 |
| Priority date | — |
| Expiry date | Aug 17, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2300/42
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
An enhanced antimicrobial antithrombogenic medical device is formed by using an oligodynamic metal and a noble metal with a polymer, and forming the mixture into a device. By using low concentrations of conductive polymers or ionophoric compounds, non-conductive, or highly plasticized polymers can be likewise blended into an iontophoretic-capable composition. The surface of the device may be treated with a solvent to remove the top surface of the polymer and create surface voids in the composition in order to expose previously encapsulated iontophoretic materials. This surface treatment results in a larger reaction area of the iontophoretic capable composition that produces larger yields of bacteriostatic oligodynamic ions for a longer duration thereby increasing the antimicrobial effectiveness of the composition. The surface of the antimicrobial composition may be treated with an anticoagulant such as heparin or heparin complexed with a quaternary ammonium salt for an added bacteriostatic effect.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.