Conversion of compactin to pravastatin by Actinomadura
US6274360A · kind A · utility
4Cited by
7References
7Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 23, 1999 |
| Grant date | Aug 14, 2001 |
| Priority date | — |
| Expiry date | Jun 23, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12R2001/03
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A method for converting compactin to pravastatin is described. Compactin is provided and contacted with an agent derived from Actinomadura under conditions in which the agent converts compactin to pravastatin. Also described are an Actinomadura strain, an Actinomadura cell free extract, an Actinomadura hydroxylase, and a method for lowering cholesterol levels in mammals.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.