Inhibition of nitric oxide synthase by amino acids and dipeptides
US6274557A · kind A · utility
6Cited by
10References
7Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 27, 1999 |
| Grant date | Aug 14, 2001 |
| Priority date | — |
| Expiry date | Oct 27, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/05
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods and compositions for inhibiting at least one isoform of nitric oxide synthase are provided. Pharmaceutical compositions include derivatives of arginine as well as dipeptides and dipeptide analogs that contain nitroarginine or another unnatural amino acid. Compositions can be used to selectively inhibit particular isoforms of nitric oxide synthase.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.