Patent · US Expired

Method of treating skin related conditions

US6274590A · kind A · utility

7Cited by
2References
13Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 14, 2000
Grant dateAug 14, 2001
Priority date
Expiry dateSep 14, 2020

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D409/04
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A class of 3,4-diaryl substituted thiophene, derivatives and analogs thereof, pharmaceutical compositions containing them and methods of using them to treat inflammation and inflammation-related disorders. Compounds of particular interest are defined by Formula I: ##STR1## wherein Y is S; wherein X is one or two substituents selected from hydrido, halo, lower alkoxycarbonyl and carboxyl; wherein R.sup.2 and R.sup.3 are independently aryl or heteroaryl; and wherein R.sup.2 and R.sup.3 are optionally substituted with one or more radicals selected from sulfamyl, alkylsulfonyl, halo, lower alkoxy and lower alkyl; or a pharmaceutically-acceptable salt thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.