Methods, compositions and articles for reducing or preventing the effects of inflammation
US6274614A · kind A · utility
Assignees
Inventors
Key dates
| Filing date | Oct 2, 1997 |
| Grant date | Aug 14, 2001 |
| Priority date | — |
| Expiry date | Oct 2, 2017 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K41/0071
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for reducing or preventing the effects of inflammation arising from injured tissue, which method comprises the steps of: a. bringing the injured tissue, or pre-injured tissue, into contact with a photosensitizing agent capable of penetrating into the tissue, resulting in the desired degree of biodistribution in less than one hour; and b. exposing the tissue thus contacted to light having a wavelength absorbed by the photosensitizing agent for a time sufficient to reduce or prevent inflammation in the exposed tissue, but not so long as to cause necrosis or erythema of the exposed tissue, or a pharmaceutical composition or an article for reducing or preventing the effects of inflammation arising from injured tissue. The composition comprises: a. from about 1 .mu./mL to about 2 mg/mL of a photosensitizing agent capable of penetrating into the injured tissue, or pre-injured tissue, resulting in the desired degree of biodistribution less than one hour; and b. a pharmaceutically acceptable carrier. The article comprises: a. a photosensitizing agent capable of penetrating into the injured tissue, or pre-injured tissue, resulting in the desired degree of biodistribution in less th…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.