Thiophene integrin inhibitors
US6274620A · kind A · utility
53Cited by
2References
38Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 7, 2000 |
| Grant date | Aug 14, 2001 |
| Priority date | — |
| Expiry date | Jun 7, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D333/38
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention comprises compounds that are effective inhibitors of integrins, particularly .alpha.v.beta.3 and .alpha.v.beta.5 integrins. Particularly, the compounds are of formula I ##STR1## and pharmaceutically acceptable salts thereof wherein X,Y.sub.1 W, R1 to R5, A and B are defined according to the disclosure herein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.