Analogs of human basic fibroblast growth factor mutated at one or more of the positions glutamute 89, aspartate 101 or leucine 137
US6274712A · kind A · utility
29Cited by
37References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 23, 1998 |
| Grant date | Aug 14, 2001 |
| Priority date | — |
| Expiry date | Dec 23, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to muteins of human basic fibroblast growth factor with superagonist properties. Both protein and the respective encoding nucleic acid species are disclosed. The invention also embodies vectors and host cells for the propagation of the nucleic acid sequences and the production of the muteins.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.