Preparation of alkali metal salts of L-ascorbic acid

US6274744A · kind A · utility

Assignee

• BASF SE

Inventors

• Wolfram Burst · Mannheim, DE
• Gerd Kaibel · Lampertheim, DE
• Andreas Böttcher · Mettmann, DE
• Veronique Kessler · Ludwigshafen, DE
• Thomas Kuntze · Böhl-Iggelheim, DE

Key dates

• Filing date: Oct 17, 2000
• Grant date: Aug 14, 2001
• Expiry date: Oct 17, 2020

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D307/62
• WIPO field: Chemical engineering
• WIPO sector: Chemistry

Abstract

A process for preparing alkali metal salts of L-ascorbic acid comprising the following steps: PA1 a) esterifying 2-keto-L-gulonic acid or diacetone-2-keto-L-gulonic acid with a C.sub.1 -C.sub.10 -alkohol in the presence of an acid catalyst, PA1 b) rearranging the resultant 2-keto-L-gulonic acid C.sub.1 -C.sub.10 -alkyl ester in the presence of an alkali metal C.sub.1 -C.sub.10 -alkoxide, comprises carrying out each of the process steps a) and b) continuously.