Method and apparatus for inactivation of biological contaminants using photosensitizers
US6277337A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 20, 1999 |
| Grant date | Aug 21, 2001 |
| Priority date | — |
| Expiry date | Jul 20, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2202/22
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Methods and apparatuses are provided for inactivation of microorganisms in fluids or on surfaces. Preferably the fluids contain blood or blood products and comprise biologically active proteins. Preferred methods include the steps of adding an effective, non-toxic amount of an endogenous photosensitizer to a fluid and exposing the fluid to photoradiation sufficient to activate the endogenous photosensitizer whereby microorganisms are inactivated. Other fluids, including juices, water and the like, may also be decontaminated by these methods as may surfaces of foods, animal carcasses, wounds, food preparation surfaces and bathing and washing vessel surfaces. Alloxazines and K- and L-vitamins are among the preferred photosensitizers. Systems and apparatuses for flow-through and batch processes are also provided for decontamination of such fluids using photosensitizers.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.