Measles virus mutant antigen
US6277380A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 4, 1999 |
| Grant date | Aug 21, 2001 |
| Priority date | — |
| Expiry date | Feb 4, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2039/53
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed is a measles virus mutant antigen consisting essentially of a measles virus mutant H protein antigen, wherein said measles virus mutant H protein antigen is at least one member selected from the group consisting of the following amino acid sequences (a) to (c): (a) an amino acid sequence of SEQ ID NO: 10; (b) an amino acid sequence of SEQ ID NO: 3 or SEQ ID NO: 11; and (c) an amino acid sequence of SEQ ID NO. 4 or SEQ ID NO: 12 By the use of the measles virus mutant antigen of the present invention, it has become possible to provide efficiently and economically a live attenuated measles vaccine which is adapted for an epidemic strain of measles virus, and a diagnostic reagent capable of accurately detecting infections with an epidemic strain of measles virus.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.