Methods for multiple direct label probe detection of multiple chromosomes or regions thereof by in situ hybridization
US6277569A · kind A · utility
34Cited by
11References
11Claims
0Family size
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Key dates
| Filing date | Jul 6, 1998 |
| Grant date | Aug 21, 2001 |
| Priority date | — |
| Expiry date | Jul 6, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6816
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Direct label probe compositions which stain DNA of a preselected single chromosome or region of a chromosome of a multi-chromosomal genome are provided that comprise mixed DNA segments which are covalently bound to fluorophore groups through linking groups. The mixed DNA segments are derived from the DNA present in the preselected chromosome or chromosome region. These probe compositions can be used concurrently or sequentially with other probe compositions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.