Cloned glutamic acid decarboxylase
US6277586A · kind A · utility
31Cited by
10References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 11, 1999 |
| Grant date | Aug 21, 2001 |
| Priority date | — |
| Expiry date | Aug 11, 2019 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/042
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides cDNA molecules comprising a part of the cDNA sequence of GAD.sub.65 which encode at least one epitope for autoantibodies to GAD.sub.65. The invention also provides cloning vehicles capable of replication and expression comprising cDNA molecules coding for GAD.sub.65. The invention further provides for hosts transformed with a vehicle having a cDNA molecule coding for GAD.sub.65. In another embodiment, the invention provides for the detection of autoantibodies to GAD.sub.65 using the GAD.sub.65 polypeptides coded for by the cDNA molecules of the invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.